Glucocerebrosidase genetic variants in Malays with early and late-onset Parkinson’s disease

• Main Authors: Pakarulrazy, Nur Fadhlina Mohamad, Syafruddin, Saiful Effendi, Mutalib, Nurul Syakima Ab, Ahmad-Annuar, Azlina, Lim, Shen Yang, Jamal, Rahman, Abdul Murad, Nor Azian, Ibrahim, Norlinah M.
• Format: Article
• Published: ASEAN Neurological Association 2020
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/25418/; https://www.neurology-asia.org/articles/neuroasia-2020-25(1)-039.pdf
• Institution: Universiti Malaya

Background: Mutations in glucocerebrosidase (GBA) have been associated with the risk of developing Parkinson’s disease (PD) in different ethnic populations. The prevalence of GBA mutations among Malay PD patients is unknown. Thus, the aim of this study was to determine the frequency of GBA mutations...