Expression of p53 N-terminal isoforms in B-cell precursor acute lymphoblastic leukemia and its correlation with clinicopathological profiles
Background: TP53 mutations occur in only about 3% of primary and 10-20% of relapse B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). However, alternative mechanisms may contribute to functionally impairing the p53 pathway in the absence of a mutation. Candidate mechanisms include overexpress...
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| Main Authors: | , , , |
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| Format: | Article |
| Published: |
BioMed Central
2020
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/25503/ https://doi.org/10.1186/s12885-020-6599-8 |
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| Institution: | Universiti Malaya |