Mechanical and fluidic analysis of hollow side-open and outer-grooved design of microneedles

• Main Authors: Ahmad, Nur Farrahain Nadia, Nik Ghazali, Nik Nazri, Wong, Yew Hoong
• Format: Article
• Published: Elsevier 2021
• Subjects: TJ Mechanical engineering and machinery
• Online Access: http://eprints.um.edu.my/26093/; https://doi.org/10.1016/j.mtcomm.2021.102940
• Institution: Universiti Malaya

This paper presents a novel concept design for microneedles that can perform dual release patterns by utilizing outer grooves as a pathway for instant delivery, dissolving body microneedles which are loaded with stimuli-responsive nanocarriers for sustained delivery and a bore for extraction diagnos...