Targeted polymeric nanoparticle for anthracycline delivery in hypoxia-induced drug resistance in metastatic breast cancer cells

• Main Authors: Almoustafa, Hassan A., Alshawsh, Mohammed A., Chik, Zamri
• Format: Article
• Published: 2021
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://eprints.um.edu.my/26204/; https://doi.org/10.1097/CAD.0000000000001065
• Institution: Universiti Malaya

Poly lactic-co-glycolic acid (PLGA) nanoparticles are intensively studied nanocarriers in drug delivery because of their biodegradability and biochemical characteristics. Polyethylene glycol (PEG) coating for nanocarriers gives them long circulation time in blood and makes them invisible to the reti...