A preliminary study on the impact of UCK2 knockdown in DLD-1 colorectal cells treated with DHODH inhibitor
Brequinar sodium ( BQR) is a well-studied inhibitor of the dihydroorotate dehydrogenase (DHODH) enzyme. Both the DHODH and uridine-cytidine kinase 2 (UCK2) enzymes have been reported to be over-expressed in cancer cells to maintain the cells high demand for DNA and RNA for their proliferation. In th...
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| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2021
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/26764/ |
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| Institution: | Universiti Malaya |