Can Zn Be a Critical Element in COVID-19 Treatment?

Can Zn Be a Critical Element in COVID-19 Treatment?

The current COVID-19 pandemic caused by SARS-CoV-2 has prompted investigators worldwide to search for an effective anti-viral treatment. A number of anti-viral drugs such as ribavirin, remdesivir, lopinavir/ritonavir, antibiotics such as azithromycin and doxycycline, and anti-parasite such as iverme...

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Main Authors: Rahman, Mohammad Tariqur, Idid, Syed Zahir
Format: Article
Published: Humana Press Inc 2021
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/27565/
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Institution: Universiti Malaya
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spelling my.um.eprints.275652022-03-10T02:52:07Z http://eprints.um.edu.my/27565/ Can Zn Be a Critical Element in COVID-19 Treatment? Rahman, Mohammad Tariqur Idid, Syed Zahir R Medicine The current COVID-19 pandemic caused by SARS-CoV-2 has prompted investigators worldwide to search for an effective anti-viral treatment. A number of anti-viral drugs such as ribavirin, remdesivir, lopinavir/ritonavir, antibiotics such as azithromycin and doxycycline, and anti-parasite such as ivermectin have been recommended for COVID-19 treatment. In addition, sufficient pre-clinical rationale and evidence have been presented to use chloroquine for the treatment of COVID-19. Furthermore, Zn has the ability to enhance innate and adaptive immunity in the course of a viral infection. Besides, Zn supplement can favour COVID-19 treatment using those suggested and/or recommended drugs. Again, the effectiveness of Zn can be enhanced by using chloroquine as an ionophore while Zn inside the infected cell can stop SARS-CoV-2 replication. Given those benefits, this perspective paper describes how and why Zn could be given due consideration as a complement to the prescribed treatment of COVID-19. Humana Press Inc 2021-02 Article PeerReviewed Rahman, Mohammad Tariqur and Idid, Syed Zahir (2021) Can Zn Be a Critical Element in COVID-19 Treatment? Biological Trace Element Research, 199 (2). pp. 550-558. ISSN 0163-4984, DOI https://doi.org/10.1007/s12011-020-02194-9 <https://doi.org/10.1007/s12011-020-02194-9>. 10.1007/s12011-020-02194-9
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Rahman, Mohammad Tariqur
Idid, Syed Zahir
Can Zn Be a Critical Element in COVID-19 Treatment?
description The current COVID-19 pandemic caused by SARS-CoV-2 has prompted investigators worldwide to search for an effective anti-viral treatment. A number of anti-viral drugs such as ribavirin, remdesivir, lopinavir/ritonavir, antibiotics such as azithromycin and doxycycline, and anti-parasite such as ivermectin have been recommended for COVID-19 treatment. In addition, sufficient pre-clinical rationale and evidence have been presented to use chloroquine for the treatment of COVID-19. Furthermore, Zn has the ability to enhance innate and adaptive immunity in the course of a viral infection. Besides, Zn supplement can favour COVID-19 treatment using those suggested and/or recommended drugs. Again, the effectiveness of Zn can be enhanced by using chloroquine as an ionophore while Zn inside the infected cell can stop SARS-CoV-2 replication. Given those benefits, this perspective paper describes how and why Zn could be given due consideration as a complement to the prescribed treatment of COVID-19.
format Article
author Rahman, Mohammad Tariqur
Idid, Syed Zahir
author_facet Rahman, Mohammad Tariqur
Idid, Syed Zahir
author_sort Rahman, Mohammad Tariqur
title Can Zn Be a Critical Element in COVID-19 Treatment?
title_short Can Zn Be a Critical Element in COVID-19 Treatment?
title_full Can Zn Be a Critical Element in COVID-19 Treatment?
title_fullStr Can Zn Be a Critical Element in COVID-19 Treatment?
title_full_unstemmed Can Zn Be a Critical Element in COVID-19 Treatment?
title_sort can zn be a critical element in covid-19 treatment?
publisher Humana Press Inc
publishDate 2021
url http://eprints.um.edu.my/27565/
_version_ 1735409520227647488

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