Comparison of anterior and posterior trabecular bone microstructure of human mandible using cone-beam CT and micro CT

• Main Authors: Ibrahim, Norliza, Parsa, Azin, Hassan, Bassam, van der Stelt, Paul, Rahmat, Rabiah A., Ismail, Siti M., Aartman, Irene H. A.
• Format: Article
• Published: BioMed Central 2021
• Subjects: RK Dentistry
• Online Access: http://eprints.um.edu.my/28602/
• Institution: Universiti Malaya

Background: The aim of this study was to compare the trabecular bone microstructures of anterior and posterior edentulous regions of human mandible using cone-beam computed tomography (CBCT) and micro computed tomography (mu CT). Methods: Twenty volumes of interests consisting of six anterior and fourteen posterior edentulous regions were obtained from human mandibular cadavers. A CBCT system with a resolution of 80 mu m (3D Accuitomo 170, J. Morita, Kyoto, Japan) and a mu CT system with a resolution of 35 mu m (SkyScan 1173, Kontich, Belgium) were used to scan the mandibles. Three structural parameters namely, trabecular number (Tb.N), trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp) were analysed using CTAn software (v 1.11, SkyScan, Kontich, Belgium). For each system, the measurements obtained from anterior and posterior regions were tested using independent sample t-test. Subsequently, all measurements between systems were tested using paired t-test. Results: In CBCT, all parameters of the anterior and posterior mandible showed no significant differences (p > 0.05). However, mu CT showed a significant different of Tb.Th (p = 0.023) between anterior and posterior region. Regardless of regions, the measurements obtained using both imaging systems were significantly different (p <= 0.021) for Tb.Th and Tb.N. Conclusions: The current study demonstrated that only the variation of Tb.Th between anterior and posterior edentulous region of mandible can be detected using mu CT. In addition, CBCT is less feasible than mu CT in assessing trabecular bone microstructures at both regions.