Specific, sensitive and rapid detection of human plasmodium knowlesi infection by loop-mediated isothermal amplification (LAMP) in blood samples

• Main Authors: Lau, Y.L., Fong, M.Y., Mahmud, R., Chang, P.Y., Palaeya, V., Cheong, F.W., Chin, L.C., Anthony, C.N., Al-Mekhlafi, A.M., Chen, Y.
• Format: Article
• Language: English
• Published: 2011
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/3240/1/Specific%2C_sensitive_and_rapid_detection_of_human.pdf; http://eprints.um.edu.my/3240/
• Institution: Universiti Malaya

Background: The emergence of Plasmodium knowlesi in humans, which is in many cases misdiagnosed by microscopy as Plasmodium malariae due to the morphological similarity has contributed to the needs of detection and differentiation of malaria parasites. At present, nested PCR targeted on Plasmodium s...