`Not at target': Prevalence and consequences of inadequate disease control in systemic lupus erythematosus-a multinational observational cohort study

• Main Authors: Kandane-Rathnayake, Rangi, Louthrenoo, Worawit, Hoi, Alberta, Luo, Shue-Fen, Wu, Yeong-Jian J., Chen, Yi-Hsing, Cho, Jiacai, Lateef, Aisha, Hamijoyo, Laniyati, Navarra, Sandra, Zamora, Leonid, Sockalingam, Sargunan, An, Yuan, Li, Zhanguo, Katsumata, Yasuhiro, Harigai, Masayoshi, Hao, Yanjie, Zhang, Zhuoli, Kikuchi, Jun, Takeuchi, Tsutomu, Basnayake, B. M. D. B., Chan, Madelynn, Ng, Kristine Pek Ling, Tugnet, Nicola, Kumar, Sunil, Oon, Shereen, Goldblatt, Fiona, O'Neill, Sean, Gibson, Kathryn A., Ohkubo, Naoaki, Tanaka, Yoshiya, Bae, Sang-Cheol, Lau, Chak Sing, Nikpour, Mandana, Golder, Vera, Morand, Eric F., Collaboration, Asia-Pacific Lupus
• Format: Article
• Published: BMC 2022
• Subjects: RC Internal medicine
• Online Access: http://eprints.um.edu.my/32744/
• Institution: Universiti Malaya

Background The unmet need in systemic lupus erythematosus (SLE) with the current standard of care is widely recognised, but few studies have quantified this. The recent definition of treat-to-target endpoints and other thresholds of uncontrolled disease activity provide an opportunity to formally de...