Successful pregnancy following aplastic anaemia.

Pregnancy following idiopathic aplastic anaemia is rare and is difficult to manage because of life-threatening episodes of bleeding and infections. Only a handful of cases has been reported in the literature. The pregnancies were unsuccessful in the majority. The present report describes a patient w...

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Bibliographic Details
Main Authors: Leong, K.W., Teh, A., Bosco, J.J., Lim, J.
Format: Article
Published: 1995
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Online Access:http://eprints.um.edu.my/343/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398268/?tool=pubmed
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Institution: Universiti Malaya
Description
Summary:Pregnancy following idiopathic aplastic anaemia is rare and is difficult to manage because of life-threatening episodes of bleeding and infections. Only a handful of cases has been reported in the literature. The pregnancies were unsuccessful in the majority. The present report describes a patient with moderately severe idiopathic aplastic anaemia who was managed with intensive haematological support leading to delivery of a healthy infant by caesarean section. Despite platelet transfusion refractoriness as a result of transfusions prior to pregnancy, adequate platelet transfusions prevented excessive bleeding. The literature is reviewed and management with platelet transfusions is discussed.