Robust radiogenomics approach to the identification of EGFR mutations among patients with NSCLC from three different countries using topologically invariant Betti numbers

• Main Authors: Ninomiya, Kenta, Arimura, Hidetaka, Chan, Wai Yee, Tanaka, Kentaro, Mizuno, Shinichi, Gowdh, Nadia Fareeda Muhammad, Yaakup, Nur Adura, Liam, Chong-Kin, Chai, Chee-Shee, Ng, Kwan Hoong
• Format: Article
• Published: Public Library of Science 2021
• Subjects: R Medicine; RC Internal medicine; RC0254 Neoplasms. Tumors. Oncology (including Cancer)
• Online Access: http://eprints.um.edu.my/34376/
• Institution: Universiti Malaya

To propose a novel robust radiogenomics approach to the identification of epidermal growth factor receptor (EGFR) mutations among patients with non-small cell lung cancer (NSCLC) using Betti numbers (BNs). Materials and methods Contrast enhanced computed tomography (CT) images of 194 multi-racial NS...