Practical considerations for using RNA sequencing in management of B-lymphoblastic leukemia Malaysia-Singapore acute lymphoblastic leukemia 2020 implementation strategy

• Main Authors: Chin, Winnie Hui Ni, Li, Zhenhua, Jiang, Nan, Lim, Evelyn Huizi, Lim, Joshua Yew Suang, Lu, Yi, Chiew, Kean Hui, Kham, Shirley Kow Yin, Oh, Bernice Ling Zhi, Tan, Ah Moy, Ariffin, Hany Mohd, Yang, Jun J., Yeoh, Allen Eng-Juh
• Format: Article
• Published: Elsevier 2021
• Subjects: R Medicine; RA Public aspects of medicine; Theories of disease. Etiology. Pathogenesis
• Online Access: http://eprints.um.edu.my/34498/
• Institution: Universiti Malaya

Despite the immense genetic heterogeneity of B-lymphoblastic leukemia or precursor B-cell acute lymphoblastic leukemia (B-ALL)], RNA sequencing (RNA-Seq) could comprehensively interrogate its genetic drivers, assigning a specific molecular subtype in >90% of patients. However, study groups have o...