Interaction of artocarpus lectins with human-iga does not involve asparagine-linked oligosaccharide of the immunoglobulin
In view of the controversy with respect to the interaction of jacalin with human IgA2, a study was undertaken to assess the reactivity of the Artocarpus heterophyllus lectin, as well as the lectin from Artocarpus integer (lectin C), with subclasses of human immunoglobulin A by ELISA. Our data is con...
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| Main Authors: | , , |
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| Format: | Article |
| Published: |
1992
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/3452/ |
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| Institution: | Universiti Malaya |
| Summary: | In view of the controversy with respect to the interaction of jacalin with human IgA2, a study was undertaken to assess the reactivity of the Artocarpus heterophyllus lectin, as well as the lectin from Artocarpus integer (lectin C), with subclasses of human immunoglobulin A by ELISA. Our data is consistent with the view that Artocarpus lectins have no affinity for the IgA2 immunoglobulins. In further support of the findings, we have established that N-linked oligosaccharide moieties of IgA have no significant bearing in the lectin-immunoglobulin binding. Interaction was also not affected in the presence of 1 (w/v) BSA. |
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