COVID-19 infection among older people admitted to hospital: A cross-sectional analysis

(1) Background: Older people with COVID-19 infection report worse clinical outcomes. There is a paucity of local data and this study aimed to describe the clinical progression of older people admitted to a university hospital in Malaysia with COVID-19 infection. (2) Methods: Older people (>= 60 y...

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Main Authors: Thiam, Chiann Ni, Hasmukharay, Kejal, Lim, Wan Chieh, Ng, Chai Chen, Pang, Gordon Hwa Mang, Abdullah, Aimy, Saedon, Nor Izzati, Khor, Hui Min, Ong, Terence
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Published: MDPI 2021
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Online Access:http://eprints.um.edu.my/34855/
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spelling my.um.eprints.348552022-05-27T03:13:21Z http://eprints.um.edu.my/34855/ COVID-19 infection among older people admitted to hospital: A cross-sectional analysis Thiam, Chiann Ni Hasmukharay, Kejal Lim, Wan Chieh Ng, Chai Chen Pang, Gordon Hwa Mang Abdullah, Aimy Saedon, Nor Izzati Khor, Hui Min Ong, Terence R Medicine (General) (1) Background: Older people with COVID-19 infection report worse clinical outcomes. There is a paucity of local data and this study aimed to describe the clinical progression of older people admitted to a university hospital in Malaysia with COVID-19 infection. (2) Methods: Older people (>= 60 years) admitted with COVID-19 infection confirmed with RT-PCR from 27 February 2020-25 May 2020 were included in this study. Data on patient characteristics, hospital treatment, and inpatient outcomes were collected via hospital-held electronic medical records. Analysis was done to describe the cohort and identify factors associated with inpatient mortality. (3) Results: 26 participants were included (mean age 76.2 years, female 57.7%). All had at least one comorbid condition and half were frail. About 19.2% had non-respiratory (atypical) symptoms; 23.1% had a severe disease that required intensive care unit monitoring; 46.2% were given COVID-19 targeted therapy. Inpatient mortality and overall complication rates were 23.1% and 42.3%, respectively. Delirium on presentation and lower Ct-value were associated with mortality (4) Conclusions: Older people with COVID-19 infection have severe infection and poor hospital outcomes. Vigilant hospital care is necessary to address their multimorbidity and frailty, along with appropriate treatment for their infection. MDPI 2021-03 Article PeerReviewed Thiam, Chiann Ni and Hasmukharay, Kejal and Lim, Wan Chieh and Ng, Chai Chen and Pang, Gordon Hwa Mang and Abdullah, Aimy and Saedon, Nor Izzati and Khor, Hui Min and Ong, Terence (2021) COVID-19 infection among older people admitted to hospital: A cross-sectional analysis. Geriatrics, 6 (1). ISSN 2308-3417, DOI https://doi.org/10.3390/geriatrics6010025 <https://doi.org/10.3390/geriatrics6010025>. 10.3390/geriatrics6010025
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Thiam, Chiann Ni
Hasmukharay, Kejal
Lim, Wan Chieh
Ng, Chai Chen
Pang, Gordon Hwa Mang
Abdullah, Aimy
Saedon, Nor Izzati
Khor, Hui Min
Ong, Terence
COVID-19 infection among older people admitted to hospital: A cross-sectional analysis
description (1) Background: Older people with COVID-19 infection report worse clinical outcomes. There is a paucity of local data and this study aimed to describe the clinical progression of older people admitted to a university hospital in Malaysia with COVID-19 infection. (2) Methods: Older people (>= 60 years) admitted with COVID-19 infection confirmed with RT-PCR from 27 February 2020-25 May 2020 were included in this study. Data on patient characteristics, hospital treatment, and inpatient outcomes were collected via hospital-held electronic medical records. Analysis was done to describe the cohort and identify factors associated with inpatient mortality. (3) Results: 26 participants were included (mean age 76.2 years, female 57.7%). All had at least one comorbid condition and half were frail. About 19.2% had non-respiratory (atypical) symptoms; 23.1% had a severe disease that required intensive care unit monitoring; 46.2% were given COVID-19 targeted therapy. Inpatient mortality and overall complication rates were 23.1% and 42.3%, respectively. Delirium on presentation and lower Ct-value were associated with mortality (4) Conclusions: Older people with COVID-19 infection have severe infection and poor hospital outcomes. Vigilant hospital care is necessary to address their multimorbidity and frailty, along with appropriate treatment for their infection.
format Article
author Thiam, Chiann Ni
Hasmukharay, Kejal
Lim, Wan Chieh
Ng, Chai Chen
Pang, Gordon Hwa Mang
Abdullah, Aimy
Saedon, Nor Izzati
Khor, Hui Min
Ong, Terence
author_facet Thiam, Chiann Ni
Hasmukharay, Kejal
Lim, Wan Chieh
Ng, Chai Chen
Pang, Gordon Hwa Mang
Abdullah, Aimy
Saedon, Nor Izzati
Khor, Hui Min
Ong, Terence
author_sort Thiam, Chiann Ni
title COVID-19 infection among older people admitted to hospital: A cross-sectional analysis
title_short COVID-19 infection among older people admitted to hospital: A cross-sectional analysis
title_full COVID-19 infection among older people admitted to hospital: A cross-sectional analysis
title_fullStr COVID-19 infection among older people admitted to hospital: A cross-sectional analysis
title_full_unstemmed COVID-19 infection among older people admitted to hospital: A cross-sectional analysis
title_sort covid-19 infection among older people admitted to hospital: a cross-sectional analysis
publisher MDPI
publishDate 2021
url http://eprints.um.edu.my/34855/
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