Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study

Objective The indiscriminate prescription of antibiotics has led to the emergence of resistance microbes worldwide. This study aimed to investigate the antibiotic prescribing practices amongst general dental practitioners and specialists in managing endodontic infections in the United Arab Emirates...

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Main Authors: B. Abraham, Sheela, Abdulla, Nizam, Wan Harun, Wan Himratul Aznita, Awad, Manal, Samaranayake, Lakshman Perera, Ahmed, Hany Mohamed Aly
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Published: PUBLIC LIBRARY SCIENCE 2020
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Online Access:http://eprints.um.edu.my/36177/
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spelling my.um.eprints.361772023-11-29T04:12:22Z http://eprints.um.edu.my/36177/ Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study B. Abraham, Sheela Abdulla, Nizam Wan Harun, Wan Himratul Aznita Awad, Manal Samaranayake, Lakshman Perera Ahmed, Hany Mohamed Aly R Medicine RK Dentistry Oral surger Objective The indiscriminate prescription of antibiotics has led to the emergence of resistance microbes worldwide. This study aimed to investigate the antibiotic prescribing practices amongst general dental practitioners and specialists in managing endodontic infections in the United Arab Emirates (UAE). Design General dental practitioners and specialists in the UAE were invited to participate in an online questionnaire survey which included questions on socio-demographics, practitioner's antibiotic prescribing preferences for various pulpal and periapical diseases, and their choice, in terms of the type, dose and duration of the antibiotic. The link to the survey questionnaire was sent to 250 invited dentists. Data were analyzed by descriptive statistics and chi-square tests for independence and level of significance was set at 0.05. Results A total of 174 respondents participated in the survey (response rate = 70%). The respondents who prescribed antibiotics at least once a month were 38.5% while 17.2% did so, more than three times a week; amoxicillin 500 mg was the antibiotic of choice for patients not allergic to penicillin (43.7%), and in cases of penicillin allergies, erythromycin 500 mg (21.3%). There was a significant difference in the antibiotic prescribing practices of GDPs compared to endodontists and other specialties especially in clinical cases such as acute apical abscesses with swelling and moderate to severe pre-operative symptoms and retreatment of endodontic cases (p<0.05). Approximately, three quarters of the respondents (78.7%) did not prescribe a loading dose when prescribing antibiotics. About 15% respondents prescribed antibiotics to their patients if they were not accessible to patients due to a holiday/weekend. Conclusions In general, the antibiotic prescribing practices of UAE dentists are congruent with the international norms. However, there were occasions of inappropriate prescriptions such as in patients with irreversible pulpitis, necrotic pulps with no systemic involvement and/or with sinus tracts. PUBLIC LIBRARY SCIENCE 2020-12 Article PeerReviewed B. Abraham, Sheela and Abdulla, Nizam and Wan Harun, Wan Himratul Aznita and Awad, Manal and Samaranayake, Lakshman Perera and Ahmed, Hany Mohamed Aly (2020) Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study. PLOS ONE, 15 (12). ISSN 19326203, DOI https://doi.org/10.1371/journal.pone.0244585 <https://doi.org/10.1371/journal.pone.0244585>. 10.1371/journal.pone.0244585
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
RK Dentistry
Oral surger
spellingShingle R Medicine
RK Dentistry
Oral surger
B. Abraham, Sheela
Abdulla, Nizam
Wan Harun, Wan Himratul Aznita
Awad, Manal
Samaranayake, Lakshman Perera
Ahmed, Hany Mohamed Aly
Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study
description Objective The indiscriminate prescription of antibiotics has led to the emergence of resistance microbes worldwide. This study aimed to investigate the antibiotic prescribing practices amongst general dental practitioners and specialists in managing endodontic infections in the United Arab Emirates (UAE). Design General dental practitioners and specialists in the UAE were invited to participate in an online questionnaire survey which included questions on socio-demographics, practitioner's antibiotic prescribing preferences for various pulpal and periapical diseases, and their choice, in terms of the type, dose and duration of the antibiotic. The link to the survey questionnaire was sent to 250 invited dentists. Data were analyzed by descriptive statistics and chi-square tests for independence and level of significance was set at 0.05. Results A total of 174 respondents participated in the survey (response rate = 70%). The respondents who prescribed antibiotics at least once a month were 38.5% while 17.2% did so, more than three times a week; amoxicillin 500 mg was the antibiotic of choice for patients not allergic to penicillin (43.7%), and in cases of penicillin allergies, erythromycin 500 mg (21.3%). There was a significant difference in the antibiotic prescribing practices of GDPs compared to endodontists and other specialties especially in clinical cases such as acute apical abscesses with swelling and moderate to severe pre-operative symptoms and retreatment of endodontic cases (p<0.05). Approximately, three quarters of the respondents (78.7%) did not prescribe a loading dose when prescribing antibiotics. About 15% respondents prescribed antibiotics to their patients if they were not accessible to patients due to a holiday/weekend. Conclusions In general, the antibiotic prescribing practices of UAE dentists are congruent with the international norms. However, there were occasions of inappropriate prescriptions such as in patients with irreversible pulpitis, necrotic pulps with no systemic involvement and/or with sinus tracts.
format Article
author B. Abraham, Sheela
Abdulla, Nizam
Wan Harun, Wan Himratul Aznita
Awad, Manal
Samaranayake, Lakshman Perera
Ahmed, Hany Mohamed Aly
author_facet B. Abraham, Sheela
Abdulla, Nizam
Wan Harun, Wan Himratul Aznita
Awad, Manal
Samaranayake, Lakshman Perera
Ahmed, Hany Mohamed Aly
author_sort B. Abraham, Sheela
title Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study
title_short Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study
title_full Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study
title_fullStr Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study
title_full_unstemmed Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study
title_sort antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study
publisher PUBLIC LIBRARY SCIENCE
publishDate 2020
url http://eprints.um.edu.my/36177/
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