Evaluation of DNA binding and topoisomerase I inhibitory activities of 16 `-Decarbomethoxydihydrovoacamine from Tabernaemontana Corymbosa
An iboga-vobasine bisindole alkaloid, 16 `-decarbomethoxydihydrovoacamine (1) isolated from the stem bark extract of Tabernaemontana corymbosa exhibited strong cytotoxicity against colorectal cancer cell lines in our preliminary study. As an initial step to elucidate its anti-proliferative mechanism...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Published: |
Wiley
2020
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/36182/ |
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| Institution: | Universiti Malaya |