Combine-ARMS: a rapid and cost-effective protocol for molecular characterization of beta-thalassemia in Malaysia

• Main Authors: Tan, K.L., Tan, J.A.M.A., Wong, Y.C., Wee, Y.C., Thong, M.K., Yap, S.F.
• Format: Article
• Language: English
• Published: 2001
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/3726/1/Combine-ARMS_A_rapid_and_cost-effective_protocol.pdf; http://eprints.um.edu.my/3726/
• Institution: Universiti Malaya

beta -Thalassemia major patients have chronic anemia and are dependent on blood transfusions to sustain life. Molecular characterization and prenatal diagnosis of beta -thalassemia is essential in Malaysia because about 4.5 of the population are heterozygous carriers for beta -thalassemia. The high...