Exploring the interaction between tyrphostin 9 and human serum albumin using biophysical and computational methods

Tyrphostin 9 (Tyr 9) is a potent platelet-derived growth factor receptor (PDGFR) inhibitor, which induces apoptosis in various cancer cell types. The binding of Tyr 9 to the major transport protein, human serum albumin (HSA) was investigated using several spectroscopic techniques and molecular docki...

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Main Authors: Kandandapani, Salanee, Ridzwan, Nor Farrah Wahidah, Mohamad, Saharuddin, Tayyab, Saad
Format: Article
Published: Taylor & Francis 2020
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Online Access:http://eprints.um.edu.my/37272/
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Institution: Universiti Malaya