Recent development of nanomaterials for transdermal drug delivery

Nano-engineered medical products first appeared in the last decade. The current research in this area focuses on developing safe drugs with minimal adverse effects associated with the pharmacologically active cargo. Transdermal drug delivery, an alternative to oral administration, offers patient con...

Full description

Saved in:
Bibliographic Details
Main Authors: Leong, Moong Yan, Kong, Yeo Lee, Burgess, Kevin, Wong, Won Fen, Sethi, Gautam, Looi, Chung Yeng
Format: Article
Published: MDPI 2023
Subjects:
Online Access:http://eprints.um.edu.my/38346/
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Universiti Malaya
Description
Summary:Nano-engineered medical products first appeared in the last decade. The current research in this area focuses on developing safe drugs with minimal adverse effects associated with the pharmacologically active cargo. Transdermal drug delivery, an alternative to oral administration, offers patient convenience, avoids first-pass hepatic metabolism, provides local targeting, and reduces effective drug toxicities. Nanomaterials provide alternatives to conventional transdermal drug delivery including patches, gels, sprays, and lotions, but it is crucial to understand the transport mechanisms involved. This article reviews the recent research trends in transdermal drug delivery and emphasizes the mechanisms and nano-formulations currently in vogue.