Neuroprotective effects of a novel peptide from Lignosus rhinocerotis against 6-hydroxydopamine-induced apoptosis in PC12 cells by inhibiting NF-kappa B activation

• Main Authors: Xiong, Chuan, Zhu, Yu, Luo, Qiang, Phan, Chia Wei, Huo, Yujie, Li, Ping, Li, Qiang, Jin, Xin, Huang, Wenli
• Format: Article
• Published: Wiley Open Access 2023
• Subjects: TP Chemical technology
• Online Access: http://eprints.um.edu.my/39448/
• Institution: Universiti Malaya

According to previous studies, oxidative stress is a leading cause of dopaminergic neuron death and may contribute to the pathogenesis of Parkinson's disease (PD). In the current study, we used chromatography of gel filtration to identify a novel peptide (Lignosus rhinocerotis peptide LRP]) fro...