Snake venomics and antivenomics of cape cobra (Naja nivea) from South Africa: Insights into venom toxicity and cross-neutralization activity

• Main Authors: Tan, Choo Hock, Wong, Kin Ying, Huang, Li-Kun, Tan, Kae Yi, Tan, Nget Hong, Wu, Wen-Guey
• Format: Article
• Published: MDPI 2022
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://eprints.um.edu.my/40312/
• Institution: Universiti Malaya

Naja nivea (Cape Cobra) is endemic to southern Africa. Envenoming by N. nivea is neurotoxic, resulting in fatal paralysis. Its venom composition, however, has not been studied in depth, and specific antivenoms against it remain limited in supply. Applying a protein decomplexation approach, this stud...