Immune checkpoint molecules and glucose metabolism in HIV-Induced T cell exhaustion

• Main Authors: Chan, Yee Teng, Cheong, Heng Choon, Tang, Ting Fang, Rajasuriar, Reena, Cheng, Kian-Kai, Looi, Chung Yeng, Wong, Won Fen, Kamarulzaman, Adeeba
• Format: Article
• Published: MDPI 2022
• Subjects: RA Public aspects of medicine; RC Internal medicine
• Online Access: http://eprints.um.edu.my/40733/
• Institution: Universiti Malaya

The progressive decline of CD8(+) cytotoxic T cells in human immunodeficiency virus (HIV)-infected patients due to infection-triggered cell exhaustion and cell death is significantly correlated with disease severity and progression into the life-threatening acquired immunodeficiency syndrome (AIDS)...