Aberrant upregulation of CDK1 contributes to medroxyprogesterone acetate (MPA) resistance in cancer-associated fibroblasts of the endometrium

The response to medroxyprogesterone acetate (MPA) decreases as endometrial disease progresses from the benign to malignancy. In a mouse model, progesterone receptor (PR) expression in normal fibroblasts is accountable for the MPA's inhibitory effects in cancer cells. However, it is still unclea...

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Bibliographic Details
Main Authors: Omar, Intan Sofia, Adenan, Noor Azmi Mat, Godoy, Alejandro, Teo, Ik Hui, Gunasagran, Yogeeta, Chung, Ivy
Format: Article
Published: Academic Press 2022
Subjects:
Online Access:http://eprints.um.edu.my/41116/
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Institution: Universiti Malaya