Antiprotozoal activity of thymoquinone (2-isopropyl-5-methyl-1,4-benzoquinone) for the treatment of leishmania major-induced leishmaniasis: In silico and in vitro studies

• Main Authors: Qureshi, Kamal A., Imtiaz, Mahrukh, Al Nasr, Ibrahim, Koko, Waleed S., Khan, Tariq A., Jaremko, Mariusz, Mahmood, Syed, Fatmi, M. Qaiser
• Format: Article
• Published: MDPI 2022
• Subjects: R Medicine; RM Therapeutics. Pharmacology
• Online Access: http://eprints.um.edu.my/41326/
• Institution: Universiti Malaya

Leishmaniasis, a neglected tropical parasitic disease (NTPD), is caused by various Leishmania species. It transmits through the bites of the sandfly. The parasite is evolving resistance to commonly prescribed antileishmanial drugs; thus, there is an urgent need to discover novel antileishmanial drug...