Typical response of CD14(++)CD16(-) monocyte to knee synovial derived mediators as a key target to overcome the onset and progression of osteoarthritis

Synovitis with increased infiltration of immune cells is observed in osteoarthritis (OA). Given the inflammatory condition of synovitis, we explored the protein profile of OA synovium (OAS) and its effect on circulating monocytes activation, migration, and functional commitments. MethodsKnee-synoviu...

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Main Authors: Saffery, Nik Syazana Izyan, Genasan, Krishnamurithy, Chan, Chee Ken, Ayob, Khairul Anwar, Teo, Seow Hui, Al-Fayyadh, Mohamed Zubair Mohamed, Othman, Iekhsan, Abidin, Syafiq Asnawi Zainal, Murali, Malliga Raman, Raghavendran, Hanumantha Rao Balaji, Kamarul, Tunku
Format: Article
Published: Frontiers Media 2022
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Online Access:http://eprints.um.edu.my/41336/
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Institution: Universiti Malaya