Autologous platelet-rich growth factor reduces M1 macrophages and modulates inflammatory microenvironments to promote sciatic nerve regeneration

• Main Authors: Yadav, Anjali, Ramasamy, Thamil Selvee, Lin, Sheng-Che, Chen, Szu-Han, Lu, Jean, Liu, Ya-Hsin, Lu, Fu-, Hsueh, Yuan-Yu, Lin, Shau-Ping, Wu, Chia-Ching
• Format: Article
• Published: MDPI 2022
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/41407/
• Institution: Universiti Malaya

The failure of peripheral nerve regeneration is often associated with the inability to generate a permissive molecular and cellular microenvironment for nerve repair. Autologous therapies, such as platelet-rich plasma (PRP) or its derivative platelet-rich growth factors (PRGF), may improve periphera...