Perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in Klang Valley, Malaysia

Endocrine disrupting chemicals (EDCs) are a growing global concern due to their widespread use and potential harm to human and animal health. Several EDCs have been linked to cancer, obesity, and diabetes in children and adults. EDCs come from manufacturers or everyday products like cookware, textil...

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Main Authors: Haron, Didi Erwandi Mohamad, Yoneda, Minoru, Hod, Rafidah, Abdul Wahab, Muhammad Ikram, Aziz, Mohd Yusmaidie
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Published: Taylor & Francis 2022
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Online Access:http://eprints.um.edu.my/41418/
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spelling my.um.eprints.414182023-09-22T03:01:14Z http://eprints.um.edu.my/41418/ Perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in Klang Valley, Malaysia Haron, Didi Erwandi Mohamad Yoneda, Minoru Hod, Rafidah Abdul Wahab, Muhammad Ikram Aziz, Mohd Yusmaidie GE Environmental Sciences Endocrine disrupting chemicals (EDCs) are a growing global concern due to their widespread use and potential harm to human and animal health. Several EDCs have been linked to cancer, obesity, and diabetes in children and adults. EDCs come from manufacturers or everyday products like cookware, textile, cosmetic, furniture, and plastic. Some EDCs are volatile and may be inhaled by the inhabitants where indoor exposure to EDCs is considered worse than outdoor exposure due to the limited and confined area allowing dermal contact and ingestion of EDCs. During the COVID-19 pandemic in 2020-2021, all Malaysians were confined to their homes, prompting the goal of this study to investigate EDCs in household dust collected from Klang Valley homes. A total of 57 dust samples were collected, filtered, and extracted using methanol. EDCs including perfluoroalkyl and polyfluoroalkyl substances (PFAS), bisphenol and parabens were identified and quantified in dust samples by liquid chromatography mass tandem spectrometry (LCMS/MS). The presence of perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), butylparaben (BuP), methylparaben (MeP), ethylparaben (EtP), and propylparaben (PrP) was detected in 50-100% of dust samples, with range of concentration of 0.31-3693.96 ng/g, indicating that these compounds are common in indoor dust. Methylparaben was the most prevalent EDC in collected dust samples with mean concentration at 148. 18 ng/g, accounting for 54% of the concentration distribution, followed by BuP and PFOA. There were regional differences in EDC profiles, with higher PFAS and paraben levels in urban areas such as Putrajaya, Kuala Lumpur, and Petaling. The estimated daily intake (EDI) of EDCs from indoor dust ingestion varied by age, with infants having a significantly higher EDI (p < .01) than children and adults. Despite safe for consumption (Hazard Quotient, HQ < 1), these findings provide a baseline for assessing PFAS, bisphenol, and paraben in indoor dust from Malaysian homes. Taylor & Francis 2022-09 Article PeerReviewed Haron, Didi Erwandi Mohamad and Yoneda, Minoru and Hod, Rafidah and Abdul Wahab, Muhammad Ikram and Aziz, Mohd Yusmaidie (2022) Perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in Klang Valley, Malaysia. Human and Ecological Risk Assessment: An International Journal, 28 (8). pp. 827-843. ISSN 1080-7039, DOI https://doi.org/10.1080/10807039.2022.2101429 <https://doi.org/10.1080/10807039.2022.2101429>. 10.1080/10807039.2022.2101429
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic GE Environmental Sciences
spellingShingle GE Environmental Sciences
Haron, Didi Erwandi Mohamad
Yoneda, Minoru
Hod, Rafidah
Abdul Wahab, Muhammad Ikram
Aziz, Mohd Yusmaidie
Perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in Klang Valley, Malaysia
description Endocrine disrupting chemicals (EDCs) are a growing global concern due to their widespread use and potential harm to human and animal health. Several EDCs have been linked to cancer, obesity, and diabetes in children and adults. EDCs come from manufacturers or everyday products like cookware, textile, cosmetic, furniture, and plastic. Some EDCs are volatile and may be inhaled by the inhabitants where indoor exposure to EDCs is considered worse than outdoor exposure due to the limited and confined area allowing dermal contact and ingestion of EDCs. During the COVID-19 pandemic in 2020-2021, all Malaysians were confined to their homes, prompting the goal of this study to investigate EDCs in household dust collected from Klang Valley homes. A total of 57 dust samples were collected, filtered, and extracted using methanol. EDCs including perfluoroalkyl and polyfluoroalkyl substances (PFAS), bisphenol and parabens were identified and quantified in dust samples by liquid chromatography mass tandem spectrometry (LCMS/MS). The presence of perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), butylparaben (BuP), methylparaben (MeP), ethylparaben (EtP), and propylparaben (PrP) was detected in 50-100% of dust samples, with range of concentration of 0.31-3693.96 ng/g, indicating that these compounds are common in indoor dust. Methylparaben was the most prevalent EDC in collected dust samples with mean concentration at 148. 18 ng/g, accounting for 54% of the concentration distribution, followed by BuP and PFOA. There were regional differences in EDC profiles, with higher PFAS and paraben levels in urban areas such as Putrajaya, Kuala Lumpur, and Petaling. The estimated daily intake (EDI) of EDCs from indoor dust ingestion varied by age, with infants having a significantly higher EDI (p < .01) than children and adults. Despite safe for consumption (Hazard Quotient, HQ < 1), these findings provide a baseline for assessing PFAS, bisphenol, and paraben in indoor dust from Malaysian homes.
format Article
author Haron, Didi Erwandi Mohamad
Yoneda, Minoru
Hod, Rafidah
Abdul Wahab, Muhammad Ikram
Aziz, Mohd Yusmaidie
author_facet Haron, Didi Erwandi Mohamad
Yoneda, Minoru
Hod, Rafidah
Abdul Wahab, Muhammad Ikram
Aziz, Mohd Yusmaidie
author_sort Haron, Didi Erwandi Mohamad
title Perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in Klang Valley, Malaysia
title_short Perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in Klang Valley, Malaysia
title_full Perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in Klang Valley, Malaysia
title_fullStr Perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in Klang Valley, Malaysia
title_full_unstemmed Perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in Klang Valley, Malaysia
title_sort perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in klang valley, malaysia
publisher Taylor & Francis
publishDate 2022
url http://eprints.um.edu.my/41418/
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