Deciphering the structural and functional impact of Q657L mutation in NLRC4 using computational methods
The NLR family caspase recruitment domain-containing protein 4 (NLRC4) inflammasome regulates the inflammatory response. Upregulation of NLRC4 inflammasome has been associated with bacterial infections, cancers, and autoinflammatory disorders (AIDs). The Q657L mutation in the NLRC4 causes AID. Howev...
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| Main Authors: | , , |
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| Format: | Article |
| Published: |
Taylor & Francis
2022
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/41448/ |
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| Institution: | Universiti Malaya |