Efficacy of international web-based educational intervention in the detection of high-risk flat and depressed colorectal lesions higher (CATCH project) with a video: Randomized trial

• Main Authors: Iwatate, Mineo, Hirata, Daizen, Francisco, Carlos Paolo D., Co, Jonard Tan, Byeon, Jeong-Sik, Joshi, Neeraj, Banerjee, Rupa, Quach, Duc Trong, Aye, Than Than, Chiu, Han-Mo, Lau, Louis H. S., Ng, Siew C., Ang, Tiing Leong, Khomvilai, Supakij, Li, Xiao-Bo, Ho, Shiaw-Hooi, Sano, Wataru, Hattori, Santa, Fujita, Mikio, Murakami, Yoshitaka, Shimatani, Masaaki, Kodama, Yuzo, Sano, Yasushi, Team, CATCH Project
• Format: Article
• Published: Wiley 2022
• Subjects: RC Internal medicine
• Online Access: http://eprints.um.edu.my/41475/
• Institution: Universiti Malaya

Objectives Three subcategories of high-risk flat and depressed lesions (FDLs), laterally spreading tumors non-granular type (LST-NG), depressed lesions, and large sessile serrated lesions (SSLs), are highly attributable to post-colonoscopy colorectal cancer (CRC). Efficient and organized educational programs on detecting high-risk FDLs are lacking. We aimed to explore whether a web-based educational intervention with training on FIND clues (fold deformation, intensive stool/mucus attachment, no vessel visibility, and demarcated reddish area) may improve the ability to detect high-risk FDLs. Methods This was an international web-based randomized control trial that enrolled non-expert endoscopists in 13 Asian countries. The participants were randomized into either education or non-education group. All participants took the pre-test and post-test to read 60 endoscopic images (40 high-risk FDLs, five polypoid, 15 no lesions) and answered whether there was a lesion. Only the education group received a self-education program (video and training questions and answers) between the tests. The primary outcome was a detection rate of high-risk FDLs. Results In total, 284 participants were randomized. After excluding non-responders, the final data analyses were based on 139 participants in the education group and 130 in the non-education group. The detection rate of high-risk FDLs in the education group significantly improved by 14.7% (66.6-81.3%) compared with -0.8% (70.8-70.0%) in the non-education group. Similarly, the detection rate of LST-NG, depressed lesions, and large SSLs significantly increased only in the education group by 12.7%, 12.0%, and 21.6%, respectively. Conclusion Short self-education focusing on detecting high-risk FDLs was effective for Asian non-expert endoscopists. (UMIN000042348).