Pharmacokinetics and metabolomic profiling of metformin and Andrographis paniculata: A protocol for a crossover randomised controlled trial

• Main Authors: Tee, Khim Boon, Ibrahim, Luqman, Mohd Hashim, Najihah, Saiman, Mohd Zuwairi, Zakaria, Zaril Harza, Zaman Huri, Hasniza
• Format: Article
• Published: MDPI 2022
• Subjects: R Medicine (General)
• Online Access: http://eprints.um.edu.my/41672/
• Institution: Universiti Malaya

This protocol aims to profile the pharmacokinetics of metformin and Andrographis paniculata (AP) and continue with untargeted pharmacometabolomics analysis on pre-dose and post-dose samples to characterise the metabolomics profiling associated with the human metabolic pathways. This is a single-cent...