Concise synthesis of the vasorelaxant alkaloids schwarzinicines A and B

A concise synthesis of the 1,4-diarylbutanoid-phenethylamine alkaloids, schwarzinicines A (1) and B (2), recently isolated from Ficus schwarzii, is reported. Key steps include a Claisen condensation to assemble the 1,4-diaryl-2-butanone intermediate, followed by a reductive amination to furnish the...

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Main Authors: Lee, Fong-Kai, Krishnan, Premanand, Muhamad, Azira, Low, Yun-Yee, Kam, Toh-Seok, Ting, Kang-Nee, Lim, Kuan-Hon
Format: Article
Published: Taylor & Francis 2022
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Online Access:http://eprints.um.edu.my/41830/
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Institution: Universiti Malaya

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