Tranexamic acid in patients undergoing noncardiac surgery

• Main Authors: Devereaux, P. J., Marcucci, M., Painter, T. W., Conen, D., Lomivorotov, V, Sessler, D., Chan, M. T., Borges, F. K., Martinez-Zapata, M. J., Wang, Chew Yin, Xavier, D., Ofori, S. N., Wang, M. K., Efremov, S., Landoni, G., Kleinlugtenbelt, Y., Szczeklik, W., Schmartz, D., Garg, A. X., Short, T. G., Wittmann, M., Meyhoff, C. S., Amir, M., Torres, D., Patel, A., Duceppe, E., Ruetzler, K., Parlow, J. L., Tandon, V, Fleischmann, E., Polanczyk, C. A., Lamy, A., Astrakov, S., Rao, M., Wu, W. K. K., Bhatt, K., de Nadal, M., Likhvantsev, V. V., Paniagua, P., Aguado, H. J., Whitlock, R. P., McGillion, M. H., Prystajecky, M., Vincent, J., Eikelboom, J., Copland, I, Balasubramanian, K., Turan, A., Bangdiwala, S., Stillo, D., Gross, P. L., Cafaro, T., Alfonsi, P., Roshanov, P. S., Belley-Cote, E. P., Spence, J., Richards, T., VanHelder, T., McIntyre, W., Guyatt, G., Yusuf, S., Leslie, K., Investigators, POISE-3
• Format: Article
• Published: Massachusetts Medical Society 2022
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/42014/
• Institution: Universiti Malaya

Background: Perioperative bleeding is common in patients undergoing noncardiac surgery. Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. Methods: We conducted a trial involving patients undergoing noncardiac surgery. Patients were randomly assigned to receive trane...