Mechanisms of natural extracts of andrographis paniculata that target lipid-dependent cancer pathways: A view from the signaling pathway

• Main Authors: Naomi, Ruth, Bahari, Hasnah, Ong, Zhi Yi, Keong, Yong Yoke, Embong, Hashim, Rajandram, Retnagowri, Teoh, Soo Huat, Othman, Fezah, Hasham, Rosnani, Yin, Khoo Boon, Kaniappan, Priyatharisni, Yazid, Muhammad Dain, Zakaria, Zainul Amiruddin
• Format: Article
• Published: MDPI 2022
• Subjects: QD Chemistry; QH301 Biology
• Online Access: http://eprints.um.edu.my/42145/
• Institution: Universiti Malaya

Andrographis paniculata is a local medicinal plant that is widely cultivated in Malaysia. It is comprised of numerous bioactive compounds that can be isolated using water, ethanol or methanol. Among these compounds, andrographolide has been found to be the major compound and it exhibits varieties of...