The therapeutic potential of gamma-Al2O3 nanoparticle containing 5-fluorouracil in the treatment of colorectal cancer

• Main Authors: Fasihi, Khadije, Amerizadeh, Forouzan, Sabbaghzadeh, Reihaneh, Heydari, Maryam, Rahmani, Farzad, Mostafapour, Asma, Khazaei, Majid, Rasouli, Elisa, Hassanian, Seyed Mahdi, Ferns, Gordon A., Rezayi, Majid, Avan, Amir
• Format: Article
• Published: Churchill Livingstone 2022
• Subjects: QH301 Biology; RC0254 Neoplasms. Tumors. Oncology (including Cancer)
• Online Access: http://eprints.um.edu.my/42342/
• Institution: Universiti Malaya

5-Fluorouracil (5-FU) is being used in the treatment of several malignancies, but side effects are often reported and include: diarrhea, vomiting, nausea, poor appetite, watery eyes, and photophobia. We have developed and tested the cytotoxic activity of nanocrystalline powder of gamma-alumina (gamm...