Heparanase gene and protein expression in ameloblastoma: possible role in local invasion of tumor cells

• Main Authors: Nagatsuka, H., Han, P.P., Tsujigiwa, H., Siar, Chong Huat, Gunduz, M., Sugahara, T., Sasaki, A., Nakajima, M., Naomoto, Y., Nagai, N.
• Format: Article
• Language: English; English
• Published: Elsevier 2005
• Subjects: RK Dentistry
• Online Access: http://eprints.um.edu.my/4291/1/Heparanase_gene_and_protein_expression_in_ameloblastoma_possible_role_in_local_invasion_of_tumor_cells.pdf; http://eprints.um.edu.my/4291/2/Heparanase_gene_and_protein_expression_in_ameloblastoma_possible_role_in_local_invasion_of_tumor_cells.pdf; http://eprints.um.edu.my/4291/; https://doi.org/10.1016/j.oraloncology.2005.01.004
• Institution: Universiti Malaya

Ametoblastoma is the most common odontogenic neoplasm, particularized by its local invasiveness. Heparanase is the endo-glucuronidase enzyme that specifically cleaves heparan sulfate, the important modulator of extracellular matrix, and related to invasion of tumor cells. In this study, we addressed...