Effect of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of acute kidney injury : a clinical research protocol for a substudy of the poise-3 randomized clinical trial

• Main Authors: Garg, Amit X., Cuerden, Meaghan, Aguado, Hector, Amir, Mohammed, Belley-Cote, Emilie P., Bhatt, Keyur, Biccard, Bruce M., Borges, Flavia K., Chan, Matthew, Conen, David, Duceppe, Emmanuelle, Efremov, Sergey, Eikelboom, John, Fleischmann, Edith, Giovanni, Landoni, Gross, Peter, Jayaram, Raja, Kirov, Mikhail, Kleinlugtenbelt, Ydo, Kurz, Andrea, Lamy, Andre, Leslie, Kate, Likhvantsev, Valery, Lomivorotov, Vladimir, Marcucci, Maura, Martínez-Zapata, Maria José, McGillion, Michael, McIntyre, William, Meyhoff, Christian, Ofori, Sandra, Painter, Thomas, Paniagua, Pilar, Parikh, Chirag, Parlow, Joel, Patel, Ameen, Polanczyk, Carisi, Richards, Toby, Roshanov, Pavel, Schmartz, Denis, Sessler, Daniel, Short, Tim, Sontrop, Jessica M., Spence, Jessica, Srinathan, Sadeesh, Stillo, David, Szczeklik, Wojciech, Tandon, Vikas, Torres, David, Van Helder, Thomas, Vincent, Jessica, Wang, Chew Yin, Wang, Michael, Whitlock, Richard, Wittmann, Maria, Xavier, Denis, Devereaux, P.J.
• Format: Article
• Published: SAGE Publications Ltd 2022
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/43163/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122518044&doi=10.1177%2f20543581211069225&partnerID=40&md5=b9f66e3970ebe6a6eec1dbfcd7945b5b
• Institution: Universiti Malaya

Background: Most patients who take antihypertensive medications continue taking them on the morning of surgery and during the perioperative period. However, growing evidence suggests this practice may contribute to perioperative hypotension and a higher risk of complications. This protocol describes...