Aducanumab therapy to treat Alzheimer's disease: A narrative review

• Main Authors: Beshir, Semira Abdi, Aadithsoorya, A.M., Parveen, Affana, Goh, Sheron Sir Loon, Hussain, Nadia, Menon, Vineetha Bharathan
• Format: Article
• Published: Hindawi Limited 2022
• Subjects: R Medicine; RA Public aspects of medicine
• Online Access: http://eprints.um.edu.my/43312/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127019773&doi=10.1155%2f2022%2f9343514&partnerID=40&md5=801b7d2ee5bb21c92387c5ef2b9dbdb4
• Institution: Universiti Malaya

Background. Aducanumab, a new monoclonal antibody that targets β-amyloid aggregates, has been granted conditional approval by the U.S. FDA for treatment of mild Alzheimer's disease (AD). The approval of this drug without a confirmed significant clinical impact has resulted in several debates. O...