Combination of polymyxin B and Aquilaria malaccensis extract enhanced the killing and inhibited the growth of Acinetobacter baumannii and Klebsiella pneumoniae

• Main Authors: Mohd Jihadi, Nurul Izzati, Maifiah, Mohd Hafidz Mahamad, Abdul Rahim, Nusaibah, Sani, Muhamad Shirwan Abdullah, Hashim, Yumi Zuhanis Has-Yun, Mohd Kamal, Khairunnisa
• Format: Article
• Published: Universiti Sains Malaysia 2022
• Subjects: QR Microbiology
• Online Access: http://eprints.um.edu.my/43337/
• Institution: Universiti Malaya

Aims: Polymyxins are an important last-line treatment for infections caused by multidrug-resistant Gram-negative bacteria. Nonetheless, the emergence of polymyxin-resistance and the limiting of polymyxin monotherapy urgently demands its optimisation. Aquilaria malaccensis (Agarwood) has been widely...