Conditioned medium of adipose-derived mesenchymal stem cells as a promising candidate to protect high glucose-induced injury in cultured C28I2 chondrocytes

• Main Authors: Safari, Sedigheh, Eidi, Akram, Mehrabani, Mehrnaz, Fatemi, Mohammad Javad, Sharifi, Ali Mohammad
• Format: Article
• Published: Tabriz University of Medical Sciences 2022
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://eprints.um.edu.my/43903/
• Institution: Universiti Malaya

Purpose: The aim of this study was to evaluate the protective effect of conditioned medium derived from human adipose mesenchymal stem cells (CM-hADSCs) on C28I2 chondrocytes against oxidative stress and mitochondrial apoptosis induced by high glucose (HG). Methods: C28I2 cells were pre-treated with...