Bisacodyl overcomes morphine-induced constipation by decreasing colonic Aquaporin-3 and Aquaporin-4 expression

Bisacodyl overcomes morphine-induced constipation by decreasing colonic Aquaporin-3 and Aquaporin-4 expression

Introduction: Morphine is an opioid prescribed to treat aches and pains. However, morphine often causes opioid-induced constipation (OIC). Aquaporin (AQP) transporters, especially AQP3 and AQP4, play an essential role in mediating constipation. Bisacodyl is a common laxative used to treat constipati...

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Main Authors: Rahmadi, Mahardian, Ardianto, Chrismawan, Nurhan, Ahmad D., Chasanah, Rafiqa A., Krismonika, Dewi I., Puspitasari, Arina D., Suprapti, Budi, Segaran, Santhra, Phan, Chia Wei, Khotib, Junaidi
Format: Article
Published: Belgorod State National Research University 2022
Subjects:
RS Pharmacy and materia medica
Online Access:http://eprints.um.edu.my/44063/
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Institution: Universiti Malaya

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http://eprints.um.edu.my/44063/

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