Indazole derivatives as selective inhibitors of butyrylcholinesterase with effective blood-brain-barrier permeability profile

Alzheimer's disease (AD) is a chronic disease that is multifactorial. Its underlying cause and mechanisms are yet to be fully understood and numerous research are underway to develop more effective drug candidates. This research explores the synthesis of an indazole-containing novel drug target...

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Main Authors: Tobuse, Asuka Joy, Law, Christine Shing Wei, Thy, Chun Keng, James, Jason Jonah, Chee, Chin Fei, Yeong, Keng Yoon
Format: Article
Published: Springer Verlag 2024
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Online Access:http://eprints.um.edu.my/44214/
https://doi.org/10.1007/s00044-023-03179-8
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Institution: Universiti Malaya