Isotonic balanced fluid versus 0.9% saline in patients with moderate to severe traumatic brain injury: A double-blinded randomised controlled trial

• Main Authors: Poh, Khadijah, Bustam, Aida, Hasan, Mohd Shahnaz, Yunos, Nor'azim Mohd, Cham, Chun Yoong, Lim, Fang Jen, Zahedi, Ahmad Zulkarnain Ahmad, Zambri, Aliyah, Azhar, Muhaimin Noor
• Format: Article
• Published: W B SAUNDERS CO-ELSEVIER INC 2024
• Subjects: RC Internal medicine; RD Surgery
• Online Access: http://eprints.um.edu.my/44226/; https://doi.org/10.1016/j.ajem.2023.11.064
• Institution: Universiti Malaya

Background and importance: Traumatic brain injury (TBI) is a global health concern with significant economic impact. Optimal fluid therapy aims to restore intravascular volume, maintain cerebral perfusion pressure and blood flow, thus preventing secondary brain injury. While 0.9% saline (NS) is comm...