Flavonoid diversity and roles in the lipopolysaccharide-mediated inflammatory response of monocytes and macrophages

• Main Authors: Rullah, Kamal, Shamsudin, Nur Farisya, Koeberle, Andreas, Tham, Chau Ling, Mohd Aluwi, Mohd Fadhlizil Fasihi, Leong, Sze Wei, Jantan, Ibrahim, Lam, Kok Wai
• Format: Article
• Published: Newlands Press Ltd 2024
• Subjects: QD Chemistry; RS Pharmacy and materia medica
• Online Access: http://eprints.um.edu.my/44965/
• Institution: Universiti Malaya

Targeting lipopolysaccharide (LPS)/toll-like receptor 4 signaling in mononuclear phagocytes has been explored for the treatment of inflammation and inflammation-related disorders. However, only a few key targets have been translated into clinical applications. Flavonoids, a class of ubiquitous plant...