Targeting mutant-p53 for cancer treatment: Are we there yet?
Background: Mutations in the TP53 gene are the most common among genetic alterations in human cancers, resulting in the formation of mutant p53 protein (mutp53). Mutp53 promotes proliferation, migration, invasion, and metastasis in cancer cells. Not only does the initiation of oncogenesis ensue due...
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Main Authors: | , , , , , , , , , , |
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Format: | Article |
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Bentham Science Publishers
2024
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Subjects: | |
Online Access: | http://eprints.um.edu.my/44987/ |
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Institution: | Universiti Malaya |