Efficacy, safety, and tolerability of adjunctive brivaracetam in adult Asian patients with uncontrolled focal-onset seizures: A phase III randomized, double-blind, placebo-controlled trial

• Main Authors: Inoue, Yushi, Tiamkao, Somsak, Zhou, Dong, Cabral-Lim, Leonor, Lim, Kheng Seang, Lim, Shih-Hui, Tsai, Jing-Jane, Moseley, Brian, Wang, Lin, Sun, Weiwei, Hayakawa, Yoshinobu, Sasamoto, Hiroshi, Sano, Tomonobu, Mcclung, Carrie, Bass, Almasa
• Format: Article
• Published: Wiley 2024
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/45329/; https://doi.org/10.1002/epi4.12929
• Institution: Universiti Malaya

Objective: The objective was to assess the efficacy and safety of adjunctive brivaracetam (BRV) with concomitant use of lamotrigine (LTG) or topiramate (TPM) in patients with uncontrolled focal seizures. Methods: Data were pooled from three randomized, placebo-controlled Phase III studies (NCT004900...