Evaluation of Lentiviral Based Gene Delivery System in Adherent and Suspension in vitro Cell Models

• Main Authors: Idris, Izyan Mohd, Nordin, Fazlina, Muhamad, Nur Jannaim, Idris, Siti Zuleha, Tye, Gee Jun, Zaman, Wan Safwani Wan Kamarul, Ng, Min Hwei
• Format: Article
• Published: Penerbit Universiti Kebangsaan Malaysia 2024
• Subjects: R Medicine; T Technology (General)
• Online Access: http://eprints.um.edu.my/45511/; https://doi.org/10.17576/jsm-2024-5303-06
• Institution: Universiti Malaya

Lentiviruses are a highly robust gene delivery system capable of in vitro and in vivo gene transfer into multiple cell types. Recent fourth-generation lentiviral systems have been designed for enhanced safety, however, the increased recombination events required to produce infective lentiviral parti...