Quinoline, Indole, and Isogranatanine Alkaloids from Malayan Leuconotis eugeniifolia

• Main Authors: Tan, Yi-Sheng, Ng, Min-Phin, Tan, Chun-Hoe, Tang, Wai-Kit, Sim, Kae-Shin, Yong, Kien-Thai, Krishnan, Premanand, Lim, Kuan-Hon, Lim, Siew-Huah, Low, Yun-Yee
• Format: Article
• Published: American Chemical Society 2024
• Subjects: QD Chemistry; RM Therapeutics. Pharmacology; RS Pharmacy and materia medica; SB Plant culture
• Online Access: http://eprints.um.edu.my/45735/; https://doi.org/10.1021/acs.jnatprod.3c00960
• Institution: Universiti Malaya

Nine new alkaloids, eugeniinalines A-H (1-8) and (+)-eburnamenine N-oxide (9), comprising one quinoline, six indole, and two isogranatanine alkaloids, were isolated from the stem-bark extract of the Malayan Leuconotis eugeniifolia. The structures and absolute configurations of these alkaloids were e...