Antibacterial performance enhancement using hydrophobic deep eutectic solvents: COSMO-RS prediction, experimental validation, and synergistic action with antibiotics

• Main Authors: Elgharbawy, Amal A. M., Khan, Huma Warsi, Noor, Najihah Mohd, Putra, Sharifah Shahira Syed, Ismail, Engku Normi Engku, Hizaddin, Hanee Farzana, Hayyan, Maan, Hayyan, Adeeb, Basirun, Wan Jefrey, Moniruzzaman, Muhammad, Al-afandi, Lama, Sani, Muhamad Shirwan Abdullah
• Format: Article
• Published: Elsevier 2024
• Subjects: QD Chemistry; TP Chemical technology
• Online Access: http://eprints.um.edu.my/45773/; https://doi.org/10.1016/j.molliq.2024.124008
• Institution: Universiti Malaya

Microbial infection is a hazardous and challenging clinical problem that has attracted considerable attention recently, primarily owing to the noticeable rise in antimicrobial resistance. To address the medical requirements to encounter this dilemma, we present hydrophobic deep eutectic solvents (HD...