Decoding the intermolecular recognition mode of a potent anticancer drug, abiraterone with human serum albumin: Assessments through spectroscopic and computational techniques

• Main Authors: Kabir, Md. Zahirul, Seng, Jane, Mohamad, Saharuddin B., Uslu, Bengi
• Format: Article
• Published: Elsevier 2024
• Subjects: QH Natural history
• Online Access: http://eprints.um.edu.my/45807/; https://doi.org/10.1016/j.molstruc.2024.137509
• Institution: Universiti Malaya

Abiraterone (ABR) is an FDA-approved anticancer drug that possesses repressing properties against the progression of advanced prostate cancer. The combination of bioactive molecules with proteins in blood circulation is the primary determinant of their potential therapeutic effectiveness. Therefore,...