Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry

• Main Authors: Ahmad, Wan Azman Wan, Ghapar, Abdul Kahar Abdul, Abidin, Hafisyatul Aiza Zainal, Karthikesan, Dharmaraj, Ross, Noel Thomas, Kader, Muhamad Ali S. K. Abdul, Loch, Alexander, Mahendran, Kauthaman, Ramli, Ahmad Wazi, Ong, Tiong Kiam, Amin, Nor Hanim Mohd, Lee, Chuey Yan, Hassan, Hamat Hamdi Che, Abidin, Siti Khairani Zainal, Liew, Houng Bang, Ho, Wing Sze, Ghazi, Azmee Mohd
• Format: Article
• Published: Wiley 2024
• Subjects: R Medicine (General)
• Online Access: http://eprints.um.edu.my/45933/; https://doi.org/10.1002/ehf2.14608
• Institution: Universiti Malaya

AimsHeart failure (HF) is a growing health problem, yet there are limited data on patients with HF in Malaysia. The Malaysian Heart Failure (MY-HF) Registry aims to gain insights into the epidemiology, aetiology, management, and outcome of Malaysian patients with HF and identify areas for improvement within the national HF services.Methods and resultsThe MY-HF Registry is a 3-year prospective, observational study comprising 2717 Malaysian patients admitted for acute HF. We report the description of baseline data at admission and outcomes of index hospitalization of these patients. The mean age was 60.2 +/- 13.6 years, 66.8% were male, and 34.3% had de novo HF. Collectively, 55.7% of patients presented with New York Heart Association (NYHA) Class III or IV; ischaemic heart disease was the most frequent aetiology (63.2%). Most admissions (87.3%) occurred via the emergency department, with 13.7% of patients requiring intensive care, and of these, 21.8% needed intubation. The proportion of patients receiving guideline-directed medical therapy increased at discharge (84.2% vs. 93.6%). The median length of stay (LOS) was 5 days, and in-hospital mortality was 2.9%. Predictors of LOS and/or in-hospital mortality were age, NYHA class, estimated glomerular filtration rate, and comorbid anaemia. LOS and in-hospital mortality were similar regardless of ejection fraction.ConclusionsThe MY-HF Registry showed that the HF population in Malaysia is younger, predominantly male, and ischaemic-driven and has good prospects with hospitalization for optimization of treatment. These findings suggest a need to reassess current clinical practice and guide resource allocation to improve patient outcomes.